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Research by Mr Cunliffe

Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial.

Garway-Heath DF, Crabb DP, Bunce C, Lascaratos G, Amalfitano F, Anand N, Azuara-Blanco A, Bourne RR, Broadway DC, Cunliffe IA, Diamond JP, Fraser SG, Ho TA, Martin KR, McNaught AI, Negi A, Patel K, Russell RA, Shah A, Spry PG, Suzuki K, White ET, Wormald RP, Xing W, Zeyen TG.

Lancet. 2015 Apr 4 ;385(9975):1295-304.

The United Kingdom Glaucoma Treatment Study: a multicenter, randomized, placebo-controlled clinical trial: design and methodology.

Garway-Heath DF, Lascaratos G, Bunce C, Crabb DP, Russell RA, Shah A; United Kingdom Glaucoma Treatment Study Investigators.

Rare case of post cataract surgery Prevotella endophthalmitis diagnosed by polymerise chain reaction DNA sequencing.

Amissah-Arthur KN, Farooq TA, Dhillon N, Cunliffe IA, Bansal A.   J Cataract Refract Surg. 2013 Mar;39(3):463-6.

Collaborators (18)

Zeyen T, Wormald R, Garway-Heath DF, Crabb DP, Bunce C, Anand N, Azuara-Blanco A, Bourne R, Broadway D, Cunliffe I, Diamond J, Fraser SG, Martin K, McNaught A, Negi A, Spry P, Amalfitano F, White E

Ophthalmology. 2013 Jan;120(1):68-76.

The accuracy of the inferior superior nasal temporal neuroretinal rim area rule for diagnosing glaucomatous optic disc damage.
Morgan JE, Bourtsoukli I, Rajkumar KN, Cunliffe IA, North RV, Wild JM.
Ophthalmology. 2012 Apr;119(4):723-30. Epub 2012 Feb 24.

Transient cardiac ischaemia and abnormal variations in systemic blood pressure in unselected primary open angle glaucoma patients.
Gherghel D, Hosking SL, Cunliffe IA, Heitmar R.
Ophthalmic Physiol Opt. 2010 Mar;30(2):175-81

A Comparison of Visual Field Progression Criteria of 3 Major Glaucoma Trials in Early Manifest Glaucoma Trial Patients.
Heijl A, Bengtsson B, Chauhan BC, Lieberman MF, Cunliffe IA, Hyman L, Leske MC.
Ophthalmology. 2008 Sep; 115(9): 1557-65. Epub 2008 Apr 18. 

Ocular response analyser to assess hysteresis and corneal resistance factor in low tension, open angle glaucoma and ocular hypertension.
Shah S, Laiquzzaman M, Mantry S, Cunliffe I.
Clin Experiment Ophthalmol. 2008 Aug;36(6):508-13.

First-line therapy with latanoprost 0.005% results in improved ocular circulation in newly diagnosed primary open-angle glaucoma patients: a prospective, 6-month, open-label study.
Gherghel D, Hosking SL, Cunliffe IA, Armstrong RA.
Eye. 2008 Mar;22(3):363-9.

Autonomic dysfunction in unselected and untreated primary open angle glaucoma patients: a pilot study.
Gherghel D, Hosking SL, Armstrong R, Cunliffe IA.
Ophthalmic Physiol Opt. 2007 Jul;27(4):336-41.

Some dissociating factors in the analysis of structural and functional progressive damage in open-angle glaucoma.
Hudson CJ, Kim LS, Hancock SA, Cunliffe IA, Wild JM.
Br J Ophthalmol. 2007 May;91(5):624-8.

Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes.
Shah S, Laiquzzaman M, Bhojwani R, Mantry S, Cunliffe IA.
Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3026-31.

Evidence for a learning effect in short-wavelength automated perimetry;
JM Wild, LS Kim, IE Pacey, IA Cunliffe.
Ophthalmology 2006; 113(2): 206-15.

A six week double-masked parallel study  of the efficacy and safety of travoprost 0.004% compared with Latanoprost 0.005% timolol 0.5% in patients with primary open angle glaucoma or ocular hypertension.
Franks WA, Renard JP, Cunliffe IA, Rojanapongpun P.
Clin Ther. 2006 Mar;28(3):332-9.

Detecting Vigabatrin toxicity by imaging of the retinal nerve fibre layer.
JM Wild, CR Robson, AL Jones, IA Cunliffe, PE Smith.
Invest Ophthalmol Vis Sci 2006; 47(3): 917-24.

Diurnal variation of ocular hysteresis in normal subjects: relevance in clinical context.
Laiquzzaman M, Bhojwani R, Cunliffe IA, Shah S.
Clin Experiment Ophthalmol. 2006 Mar;34(2): 114-8.

Objective accommodative amplitude and dynamics with the 1CU accommodative intraocular lens.
JS wolffsohn, OA Hunt, SA Naroo, S Shah,  B Gilmartin, IA Cunliffe, MT Benson, S Mantry.
Invest Ophthalmol Vis Sci 2006; 47(3): 1230-5.

Subjective and objective performance of the lenstec kh3500 accommodative intraocular lens.
Wolffsohn JS. Naroo SA, Motwani NK, Shah S, Hunt OA, Mantry S, Sira M, Cunliffe IA, Benson M.
Br J Ophthalmol 2006 ; Mar :10

The use of the Reichert ocular response analyser to establish the relationship between ocular hysteresis, corneal resistance factor and central corneal thickness in normal eyes
Shah S, Laiquzzaman M, Cunliffe IA, Mantry S.
Cont Lens Anterior Eye. 2006 Dec;29(5):257-62. Epub 2006 Nov 7.

Beneficial effects of small-incision cataract surgery in patients demonstrating reduced ocular blood flow.
EJ Hilton, SL Hosking, D Gherghel, S Embleton, IA Cunliffe.
Eye 2005; 19(6): 670-5.

Systemic reduction in glutathione levels occurs in patients suffering from Primary open angle glaucoma.
D Gherghel, H Griffiths, E Hilton, IA Cunliffe, S Hoskins.
Investigative Ophthalmol Vis Sci 2005; 46: 877-883.

Correlatuion of Nidek OPD Scan objective refraction with subjective refraction.
Yeung IY, Mantry S, Cunliffe IA, Benson MT, Shah S.
J Refract Surg. 2004 Sep-Oct;20(5 Suppl):S734-6

Abnormal systemic and ocular vascular response to temperature provocation in primary open angle glaucoma patients. A case for autonomic failure?
D Gherghel, SL Hosking, IA Cunliffe.
Investigative Ophthalmol Vis Sci 2004 ; 45 : 3546-3554.

A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, elevator-masked, multicentre study in Europe.
J Garcia-Sanchez, JF Rouland, D Spiegel, B Pajic, IA Cunliffe, C Traverso, J Landry
Br J Ophthalmol 2003.

Higher order aberrations with aspheric ablations using the Nidek EC-5000 CX II Laser.
Yeung IY, Mantry S, Cunliffe IA, Benson MT, Shah S.
J Refract Surg. 2004 Sep-Oct;20(5 Suppl):S659-62.

Perimetric fatigue is not dependent on threshold algorithm.
I Pacey, JM Wild, IA Cunliffe.
Invest Ophthalmol Vis Sci  2003 (suppl); 58.

Longitudinal changes in function and structure in primary open angle glaucoma and ocular hypertension.
LS Kim, JM Wild, S Hancock, IA Cunliffe.
Invest Ophthalmol Vis Sci  2003 (suppl); 66.

Acute angle closure glaucoma
IA Cunliffe
Post-Graduate Diploma in Practical Ophthalmology Module 1 Topic 4. Rila Publications Ltd. 2003.

Longitudinal changes in function and structure in primary open angle glaucoma and ocular hypertension
LS Kim, JM Wild, S Hancock, IA Cunliffe
Invest Ophthalmol Vis Sci 2003 (suppl); 66

IOP and glaucoma
IA Cunliffe
Optician 2003 ; 225 : 14-16

New Drugs in glaucoma therapy
IA Cunliffe
Hospital medicine 2003 ; 64 (3) : 156-159

Balancing power and control in glaucoma therapy
AS Crandall, P Schacknow, H Barneby, IA Cunliffe, S Miglior, M Teus, J Przydryga
Ocular Surgery News 2003; 3-15. Slack Incorporated.

Ocular Blood flow perfusion characteristics following cataract surgery
IA Cunliffe
, EJ Roff-Hilton, D Gherghel, SL Hoskins
Invest Ophthalmol Vis Sci 2002 (suppl); 371

Lumigan (bimatoprost) : a clinical review
IA Cunliffe
Eye News 2002; vol 9, No2.

Plasma vascular endothelial growth factor, soluble VEGF receptor FLT-1, and Von Willibrand factor in glaucoma.
Lip Pl, Felmeden DC, Blann AD, Matheou N, Thakur S, Cunliffe IA, Lip GY.
Br J Ophthalmology 2002 ; 86(11) : 1299-302.

Travoprost a clinical review
IA Cunliffe
Protecting Vision. 2nd Alcon Scientific Symposium 2002 ; 9-11. Alcon Laboratories UK Ltd.

Effect of senescence on ocular blood flow in the retina, neuroretinal rim and lamina cribrosa, using scanning laser Doppler flowmetry
Embleton SJ, Hosking SL, Roff Hilton EJ, Cunliffe IA
Eye 2002; 16(2): 156-62.

Application of a local search strategy improves the detection of blood flow deficits in the neuroretinal rim of glaucoma patients using scanning laser Doppler flowmetry
Hoskins SL, Embleton SJ, Cunliffe IA
Br J Ophthalmol 2001; 85(11): 1298-302 2002 ; 16(2) : 156-62

Visual field loss attributable to misting of the trial lens
N Matheou, G Sedgwick, JM Wild, IA Cunliffe
Acat Ophthalmologica 2000;78(6): 721-722.37

Is the role of trabeculectomy in glaucoma management changing?
KW Whittaker, T Gillow, IA Cunliffe
Eye 2001; 15 : 449-452

The SITA perimetric threshold algorhythms in glaucoma
JM Wild, IE Pacey, EC O’Neill, IA Cunliffe
Invest Ophthalmol Vis Sci 1999; 40: 1998-2009

New medications in glaucoma
IA Cunliffe
IGA Summer Journal 1999

Glaucoma – Current treatment
IA Cunliffe
National Association of Primary Care Official Review 1999; 308-309

A closer look at Brimonidine
IA Cunliffe
Independent Health Facilities 1999; 58-58

Between-algorithm, between individual differences in normal perimetric sensitivity: full threshold, FASTPAC, and SITA
JM Wild, IE Pacey, SA Hancock, IA Cunliffe
Invest Ophthalmol Vis Sci 1999; 40: 1152-1161

Light and ultrastructural microscopy of Molteno drains
ACB Molteno, AG Dempster, IA Cunliffe
Invest Ophthalmol Vis Sci 1996 (suppl); S422.

Clinical Update: Ophthalmology
IA Cunliffe
The RCGP Members Reference Book 1998/99; 231-234. Ed. D Garvie, Campden Publishing Ltd.

Suprachoroidal haemorrhage. Editorial
IA Cunliffe
Eye 1998; 12: 755-756.

The between subject, between alogrithm variability of normal sensitivity with the SITA standard and the SITA fast threshold alogrithms
IE Pacey, JM Wild, RP Cubbidge, S Hancock, IA Cunliffe
Invest Ophthalmol Vis Sci 1998 (suppl); S493.

The between visit reproducibility of white on white automated perimetry, short wavelength automated perimetry, and frequently doubling perimetry
S Hancock, JM Wild, IA Cunliffe
Invest Ophthalmol Vis Sci 1998 (suppl); S26.

The validity and reproducibility of the SITA standard and the SITA fast threshold algorithms in glaucoma
IA Cunliffe
, IE Pacey, JM Wild, G Sedgwick, EC O’Neil
Invest Ophthalmol Vis Sci 1998 (suppl); S26.

Glaucoma. The aetiology and pathology of glaucoma
N Anand, IA Cunliffe
Hospital Pharmacist 1998; 5: 73-75

Long term follow up of Molteno drains in the treatment of glaucoma presenting in childhood
IA Cunliffe
, ACB Molteno
Eye 1998; 12: 379-385.

The effect of TGF-betal and TGF-beta 2 on the proliferation of human Tenons capsule fibroblasts in tissue culture
IA Cunliffe
, RC Rees, IG Rennie
Ophthalmology Digest 1996; 5: 12-13.

The effect of TGF-betal and TGF-beta 2 on the proliferation of human Tenons capsule fibroblasts in tissue culture
IA Cunliffe
, RC Rees, IG Rennie
Acta Ophthalmologica 1996; 74: 31-35

The effect of TNF, IL-1 and IL-6 on the proliferation of human Tenons capsule fibroblasts in tissue culture
IA Cunliffe
, PR Richardson, RC Rees, IG Rennie
British Journal of Opthalmology 1995; 79: 590-595

The effect of topical cholinergic medications on the proliferation and viability of human Tenons capsule fibroblasts in tissue culture
IA Cunliffe
, CA McIntyre, RC Rees, IG Rennie
Great Archives for Clinical and Experimental Ophthalmology 1995; 233: 507-512

The effect of topical beta-blocker medications on the function of tenons capsule fibroblasts in tissue culture
IA Cunliffe
, CA McIntyre, RC Rees, IG Rennie
German journal of Ophthalmology 1995; 4: 167-174

A pilot study on the effect of topical adrenergic medications on the proliferation and viability of Tenons capsule fibroblasts in tissue culture
IA Cunliffe
, CA McIntyre, RC Rees, IG Rennie
British Journal of Opthalmology 1995; 79: 70-75

The effect of TNF, IL-1, and IL-6 on the proliferation of human Tenons capsule fibroblasts in tissue culture
IA Cunliffe
, PR Richardson, RC Rees, IG Rennie
Invest Ophthalmol Vis Sci 1994; 35: 1433

The influence of apraclonidine and pilocarpine alone and in combination on post-laser trabeculectomy pressure rise
RB Dapling, IA Cunliffe, S Longstaff
British Journal of Ophthalmology 1994; 78: 30-32.15

The effect of trabeculectomy on corneal topography
IA Cunliffe
, RB Dapling, J West, S Longstaff
Ophthalmic Surg 1993; 24: 135

Does heparin surface modification affect the incidence of inflammatory related complications in patients with glaucoma undergoing endocapsular cataract extraction with posterior chamber lens implantation
IA Cunliffe
, J West, S Longstaff
Eur J Ref Surg 1993; 5: 219-223

Factors contributing to early post-operative visual changes following trabeculectomy
IA Cunliffe
, RB Dapling, S Longstaff
Invest Ophthalmol Vis Sci 1992; 33: 1271

Prevention of acute post-operative pressure rises in glaucoma patients undergoing cataract extraction with posterior chamber lens implant
J West, J Burke, IA Cunliffe, S Longstaff
British Journal of Ophthalmology 1992; 76: 534-537

A prospective study examining the changes in factors that affect visual acuity following trabeculectomy
IA Cunliffe
, RD Dapling, J West, S Longstaff
Eye 1992; 6: 618-622

Bilateral optic nerve sheath meningiomas in a patient with neurofibromatosis type 2
IA Cunliffe
, D Hardy, D Moffat, AT Moore
British Journal of Ophthalmology 1992; 76: 310-312

Retained intraocular foreign body simulating choroidal melanoma
IA Cunliffe
, A Singh, C Mody, J Innes, IG Rennie
German Journal of Ophthalmology 1991; 2: 416-418

Extracapsular cataract surgery with lens implantation in diabetics with and without retinopathy
IA Cunliffe
, NDL George, DW Flannagan, AT Moore
Ophthalmology Digest 1991; 7: 22-23

A novel approach to the assessment of afferent pupillary defects
MT Benson, ME Nelson, IA Cunliffe, IG rennie.
Eye 1991;5: 40-44.

Extracapsular cataract surgery with lens implantation in diabetics with and without retinopathy
IA Cunliffe
, NDL George, DW Flannagan, AT Moore
British Journal of Ophthalmology 1991; 75: 9-12